Prozac Vs. Zoloft Explained

Prozac and Zoloft are antidepressants that are used to treat a number of psychological disorders. They contain selective serotonin reuptake inhibitors or SSRIs that act to rebalance the chemicals in the brain. Their effect on serotonin, a neurotransmitter that creates a feeling of happiness and well-being, is particularly profound. These two drugs are often compared because of their similarities but they have significant differences as well.

Similarities

Both are 2nd generation anti-depressants that are safer than those that came before them. They are unlikely to cause weight gain and do not have a sedating effect. These SSRIs are often prescribed for depression as they have been found to relieve symptoms in up to 70% of the cases. Their levels of effectiveness are fairly even with no study conclusively favoring one over the other for major depression. Doctors can prescribe either depending on the exact diagnosis. It is difficult to know which one is best for an individual so they generally recommend what they think is a better fit, start with a low dosage, and observe for side effects.

Applications

Prozac is used to treat bulimia nervosa, panic disorder, obsessive compulsive disorder, and major depressive disorder in adults. It is also approved for treating children with depression ages 8 and up, as well as children with OCD ages 7 and up. Meanwhile, Zoloft is used for the treatment of social anxiety disorder, severe premenstrual syndrome, post traumatic stress disorder, panic attacks, obsessive compulsive disorder, and major depression in adults. It is also suitable for children with OCD with ages 6 and up. Note that these drugs take time to work. Expect to take them religiously for up to four weeks before feeling the changes.

Differences

Prozac and Zoloft are available in low doses that are suitable for daily intake. However, only Prozac can be prescribed for a strong weekly dose. Their other differences lie in their side effects. Using Zoloft increases the chances of experiencing diarrhea more so than Prozac does. This might become an issue for people who are prone to stomach distress like those with IBS. On the other hand, Prozac has a higher tendency to cause sleep disturbances and dry mouth.